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Table 3 Multivariate proportional hazard ratio for oral and pharyngeal carcinoma death in Taiwan from 1985–1994.

From: Prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan

 

Oral and pharyngeal carcinoma death (N = 4106)

Ethnic group

Aborigines community (N = 130)

Hakka community (N = 215)

Hokkien community (N = 3761)

Characteristics

HR(95% CI)

HR(95% CI)

HR(95% CI)

Period of diagnosis (yrs)

   

   1985–1989

1.00

1.00

1.00

   1990–1994

1.43(0.93–2.20)

1.55(1.13–2.13)*

1.20(1.12–1.29)*

Gender

   

   Females

1.00

1.00

1.00

   Males

0.94(0.62–1.43)

1.87(1.18–2.97)*

1.60(1.42–1.81)*

Diagnostic age (yrs)

   

   < = 49

1.00

1.00

1.00

   50–59

1.17(0.71–1.92)

1.12(0.77–1.61)

0.96(0.89–1.04)

   60–69

1.24(0.74–2.08)

1.19(0.83–1.73)

0.99(0.90–1.08)

   > = 70

1.05(0.59–1.87)

2.46(1.62–3.73)*

1.15(1.03–1.28)*

Anatomic site

   

   Oropharyngeal

1.00

1.00

1.00

   Lip

1.22(0.33–4.55)

0.52(0.17–1.61)

0.77(0.61–0.98)*

   Tongue

0.94(0.37–2.37)

1.36(0.77–2.41)

1.31(1.14–1.50)*

   Mouth

0.89(0.37–2.15)

1.18(0.67–2.07)

1.26(1.10–1.43)*

   Hypopharyngeal

0.43(0.17–1.11)

0.99(0.51–1.90)

0.98(0.84–1.15)

   Other

0.00-a

0.85(0.11–6.77)

0.70(0.43–1.13)

Morphologic type

   

   SCC

1.00

1.00

1.00

   Verrucous carcinoma

0.95(0.38–2.40)

0.46(0.20–1.05)

0.51(0.42–0.62)*

   Other carcinoma

0.63(0.30–1.35)

0.35(0.20–0.62)*

0.54(0.47–0.62)*

Therapy

   

   Surgery alone

1.00

1.00

1.00

   RT alone

3.02(1.25–7.28)*

3.03(1.70–5.40)*

2.61(2.26–3.01)*

   CT alone

1.38(0.55–3.46)

4.81(2.93–7.90)*

2.74(2.41–3.12)*

   Surgery + RT

2.01(0.98–4.13)

1.56(0.85–2.84)

1.76(1.55–2.01)*

   Surgery + CT

1.21(0.46–3.13)

2.40(1.30–4.45)*

1.38(1.18–1.61)*

   RT + CT

5.38(2.26–12.83)*

2.97(1.55–5.67)*

3.49(3.02–4.03)*

   Surgery + RT + CT

3.76(1.60–8.83)*

4.59(2.51–8.39)*

2.58(2.20–3.01)*

   ST alone

3.78(1.69–8.43)*

2.55(1.11–5.86)*

3.05(2.53–3.69)*

   Other complex therapy

2.96(1.57–5.59)*

2.46(1.61–3.74)*

2.09(1.89–2.30)*

  1. SCC: squamous cell carcinoma; RT: radiation therapy; CT: chemotherapy; ST: supportive care therapy.
  2. HR: hazard ratio; CI: confidence interval.
  3. a No subjects died from other anatomic site.
  4. *Statistical significance (p < 0.05).