Table 6 Gene expression of T-est cells in relation to MSSM cells 25 Significant Down-regulated Genes in T-est cells
From: Transcription profiles of non-immortalized breast cancer cell lines
| Â | SAM | Atlas | Â | Â | ||
|---|---|---|---|---|---|---|
Name | Score(d) | Fold | Ratio | Diff. | Protein/gene | Gene ontology |
FES | -7.9514 | -1063.830 | Down | -1081 | C-fes proto-oncogene | cell communication cellular physiological process metabolism |
VIM | -7.0022 | -5.070 | -3.698 | -9614 | vimentin | Gen with GO but NOT at level 3 biological process |
TGFBI | -6.6491 | -22.619 | -17.180 | -6844 | BIGH3 | cell communication cellular physiological process regulation of cellular process response to stimulus |
BMP1 | -6.5296 | -12.975 | -9.085 | -1609 | bone morphogenetic prot. 1+ procollagen C-proteinase | metabolism |
MLH1 | -6.4271 | -9.043 | -6.664 | -1552 | mutL protein homolog; DNA mismatch repair protein | cellular physiological process metabolism response to stimulus |
LAMA4 | -6.3501 | -24.913 | -19.264 | -2630 | laminin alpha 4 subunit precursor | cell communication |
MMP11 | -6.2022 | -6.609 | -5.019 | -24432 | matrix metalloproteinase 11; stromelysin 3 | metabolism |
TIMP1 | -6.1061 | -6.355 | -4.793 | -26048 | metalloproteinase inhibitor 1 | cellular physiological process metabolism regulation of cellular process |
PLXNA3 | -5.9530 | -3.489 | -2.845 | -2334 | transmembrane protein sex precursor | Gen with GO but NOT at level 3 biological process |
TIMP2 | -5.1069 | -6.041 | -4.092 | -1274 | tissue inhibitor of metalloproteinases 2 | cellular physiological process |
ITGB8 | -5.0533 | -12.188 | -8.712 | -2414 | integrin beta 8 | cell communication |
ITGB3 | -4.8610 | -1282.051 | Down | -1259 | integrin beta 3 | cell communication |
SPARC | -4.7998 | -2857.143 | Down | -2997 | secreted protein acidic and rich in cysteine precursor; osteonectin | physiological process |
FN1 | -4.5334 | -50.633 | -34.784 | -10608 | fibronectin precursor | cell communication cellular physiological process metabolism response to stimulus |
MMP9 | -4.5288 | -12.126 | -7.859 | -1365 | matrix metalloproteinase 9 | metabolism |
HSPG2 | -4.3027 | -1149.425 | Down | -1164 | heparan sulfate proteoglycan | cell communication |
MMP14 | -4.0581 | -5.566 | -3.840 | -2454 | matrix metalloproteinase 14; MT- MMP1 | metabolism |
ITGA5 | -3.9413 | -11.151 | -7.838 | -3836 | integrin alpha 5 | cell communication |
MT3 | -3.9295 | -7.365 | -5.866 | -9946 | metallothionein-III | cellular physiological process metabolism regulation of cellular process response to stimulus |
DAB2 | -3.8058 | -1190.476 | Down | -1232 | mitogen-responsive phosphoprotein DOC2 | cellular physiological process |
SERPINB2 | -3.6797 | -1818.182 | Down | -1773 | placental plasminogen activator inhibitor 2 (PAI-2); urokinase inhibitor | cellular physiological process regulation of cellular process |
IGFBP6 | -3.6326 | -12.402 | -8.758 | -1668 | insulin-like growth factor binding protein 6 precursor | cell communication cellular physiological process regulation of cellular process |
COL6A1 | -3.6304 | -8.586 | -6.311 | -2767 | collagen 6 alpha 1 subunit (COL6A1) | cell communication cellular physiological process |
IL6 | -3.4586 | -10.628 | -7.933 | -2586 | interleukin-6 precursor | cell communication cellular physiological process regulation of cellular process response to stimulus |
LIF | -3.4166 | -5.400 | -3.940 | -1085 | leukemia inhibitory factor precursor | cell communication cellular physiological process regulation of cellular process response to stimulus |