Table 3 The ORs for CRC of APC genotypes at g.1458T>C, g.4479G>A, g.5268T>G and g.5465A>T.
Variant | Genotype | Numbers in healthy/patient group | OR (95% CI$) | p* |
|---|---|---|---|---|
g.1458T>C | TT | 2/5 | 1.65 (0.31 – 8.93) | NS# |
|  | TC | 31/13 | 0.28 (0.13 – 0.59) | 0.001 |
| Â | CC | 41/62 | 1 | Â |
g.4479G>A | GG | 2/0 | 0 | NS |
|  | GA | 23/11 | 0.34 (0.15 – 0.76) | 0.009 |
| Â | AA | 49/69 | 1 | Â |
g.5268T>G | TT | 7/0 | 0 | NS |
|  | TG | 23/17 | 0.52 (0.25 – 1.08) | 0.078** |
| Â | GG | 44/63 | 1 | Â |
g.5465A>T | AA | 64/78 | 1 | Â |
|  | AT | 10/2 | 0.16 (0.03 – 0.78) | 0.023 |
| Â | TT | 0/0 | Â | Â |