Table 3 Analysis of COX-2 8473T>C genotype frequencies, ORs and 95% CIs for adenocarcinoma by selected variables

Gender

   Male

86 (68.2)

35 (27.8)

5 (4.0)

0.61 (0.40–0.93)^a

0.59 (0.39–0.91)^a,b

   Female

51 (64.6)

25 (31.7)

3 (3.8)

0.71 (0.40–1.29)

0.72 (0.40–1.30)^b

Age (years)

   ≤60

69 (62.7)

39 (35.5)

2 (1.8)

0.73 (0.46–1.14)

0.74 (0.47–1.16)^c

   >60

68 (71.6)

21 (22.1)

6 (6.3)

0.56 (0.34–0.92)^a

0.55 (0.33–0.93)^c,d

Smoking status

   Never

49 (61.2)

28 (35.0)

3 (3.8)

0.80 (0.46–1.40)

0.77 (0.43–1.36)^c

   Ever^f

88 (70.4)

32 (25.6)

5 (4.0)

0.56 (0.36–0.85)^g

0.57 (0.37–0.87)^e,g

Pack-years in ever-smokers^f

   ≤35 pys

46 (74.2)

14 (22.6)

2 (3.2)

0.50 (0.27–0.93)^d

0.51 (0.27–0.96)^e,h

   >35 pys

42 (66.7)

18 (28.6)

3 (4.8)

0.60 (0.33–1.08)

0.60 (0.33–1.10)^e