Table 4 The effects of filtering for SNPs and redundant substitutions on the substitution spectra
From: Signs of positive selection of somatic mutations in human cancers detected by EST sequence analysis
| Â | Raw data | After removing SNPs | After removing redundant mutations | |||
|---|---|---|---|---|---|---|
| Â | # spectra (ESTs with substitutions) | # substitutions | # spectra (ESTs with substitutions) | # substitutions | # spectra (ESTs with substitutions) | # substitutions |
Cancer | 13961 | 388381 | 13961 | 311756 | 10305 | 253634 |
Normal | 17116 | 736031 | 17116 | 527018 | 10352 | 410800 |