Quantitative real-time RT-PCR validation of differential mRNA expression of SPARC, FADD, Fascin, COL7A1, CK4, TGM3, ECM1, PPL and EVPLin esophageal squamous cell carcinoma

Table 4 mRNA expression of nine genes in ESCC patients by family history of uppergastrointestinal cancer

Gene	Total number of cases	Median of N-fold mRNA expression
		FH (+) cases (N = 23)	FH (-) cases (N = 52)	P-value**
*SPARC*	75	5.3394	3.8266	0.099
*FADD*	75	4.2772	2.9452	0.125
*Fascin*	71*	6.7426	4.7068	0.515
*COL7A1*	75	3.6892	2.7104	0.904
*CK4*	75	0.0116	0.0378	0.143
*TGM3*	75	0.0028	0.0312	0.060
*ECM1*	75	0.0213	0.0938	0.038
*PPL*	75	0.1205	0.3353	0.044
*EVPL*	75	0.1247	0.3847	0.082

ISSN: 1471-2407