A non-randomised, single-centre comparison of induction chemotherapy followed by radiochemotherapy versus concomitant chemotherapy with hyperfractionated radiotherapy in inoperable head and neck carcinomas

Table 3 Comparison of responses in dependency on the schedule

	SEQ (n = 70)				CON (n = 52)
	After 2 cycles chemotherapy		After chemotherapy and radiotherapy		After chemotherapy and radiotherapy
	Primary (%)	Nodes (%)	Primary (%)	Nodes (%)	Primary (%)	p²⁾	Nodes (%)	p²⁾
Evaluable	93 (65/70)	93 (65/70)	89 (62/70)	86 (60/70)	98 (51/52)	0.02	98 (51/52)	0.00
Complete response ¹⁾ (CR)	11	7	41	33	46	n.s.	58	n.s.
Partial remission ¹⁾ (PR)	51	51	26	33	44	n.s.	37	n.s.
CR and PR	63	59	67	66	90	n.s.	94	n.s.
NC, Progressive disease	30	33	21	20	8	n.s.	4	n.s.

¹⁾ WHO
²⁾ compared with response in the SEQ-group after chemotherapy and radiotherapy

ISSN: 1471-2407