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Table 4 Comparison of accelerated or hyperfractionated radiotherapy with conventionally fractionated radiotherapy (Group 2/3)

From: A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck

  

control arm

experimental arm

  

publication

trial #

dose [Gy]

RT time [days]

dose [Gy]

RT time [days]

fractionation

Stage 4 [%]

N3 [%]

group 2

 

conventional fract.

acceleration

  

Dische [16]

20

66

45.5

54

12

CHART

72

6

Dobrowsky [37]

21

70

49.0

55.3

17

CHART

 

12

Olmi [41]

22

68

47.3

65.6

42.7

AF split

70

7

Fu [42]

23

70

49.0

67.2

43.4

AF split

68

13

v. den Bogaert [43]

24

72.5

56.0

69.6

44.8

AF split

65

47

Horiot [23]

25

70

51.7

72

35

AF split

0

0

Fu [42]

26

70

49.0

72

42

concomittant boost

  

Overgaard [44]

27

66–68

39.0

66–68

46.0

weekend

25

 

Skladowsky [13]

28

70.6

54

70.75

40

weekend

17

0

group 3

 

conventional fract.

hyperfractionation

  

Sanchiz [18]

29

60

42.0

70.4

44.8

HFX

 

30

Pinto [45]

30

66

46.2

70.4

44.8

HFX

54

25

Horiot [46]

31

70

51.1

80.5

49

HFX

 

15

Fu [42]

32

70

49.0

81.6

47.6

HFX

68

13

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BMC Cancer

ISSN: 1471-2407

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