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Figure 5 | BMC Cancer

Figure 5

From: BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility

Figure 5

Adhesion on endothelium and endothelial transmigration of hematopoietic progenitor 32D cells expressing t(9;22) translocation products. A. Percentage of 32D cells that were adherent to HUVEC in the absence/presence (-/+) of TNFα under different shear stresses (0.1 and 2 dyn/cm2) in a flow chamber. The bar graphs represent the averages of three fields counted with standard deviation. One representative experiment out of three performed is given. B. Percentage of 32D cells that migrated through a HUVEC layer in a transwell assay. The bar graphs represent the average of triplicates with standard deviation. One representative experiment out of three performed is given.

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