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Table 1 Features of the breast cancer cases1

From: Association of MTHFR gene polymorphisms with breast cancer survival

Age at diagnosis (mean ± SD; n = 248)

55.0 ± 13.9

Body mass index (mean ± SD; n = 248)

29.1 ± 8.0

 

N (%)

Race/Ethnicity

 

   African-American

143 (58)

   Caucasian

105 (42)

Menopausal status at diagnosis

 

   Pre-menopausal

64 (31)

   Post-menopausal

141 (69)

Alcohol consumption

 

   No

93 (41)

   Yes

133 (59)

Survival

 

   Alive

189 (76)

   Deceased2

59 (24)

Tumor histology

 

   Ductal

189 (76)

   Lobular

34 (14)

   Others

25 (10)

Node status

 

   Negative

144 (63)

   Positive

84 (37)

Stage at diagnosis (TNM)

 

   ≤ Stage I

66 (29)

   Stage II

118 (52)

   ≥ Stage III

44 (19)

Chemotherapy

 

   No

99 (43)

   Yes3

132 (57)

Neoadjuvant therapy

 

   No

178 (77)

   Yes

53 (23)

Estrogen receptor-α

 

   Negative

102 (41)

   Positive

145 (59)

HER2/neu

 

   Low to weak

154 (62)

   Moderate to strong

93 (38)

  1. 1 Cases with missing information are not included. SD = standard deviation. Race/ethnicity is determined by self-identification. Pre-menopausal: still having menstruation. Post-menopausal: 55 years or older, or stated change of life, or hysterectomy with both ovaries removed. Alcohol consumption: yes if > 12 drinks in life at time of recruitment. 2 For 5 patients, the cause of death was not breast cancer. 3 Includes neoadjuvant therapy