From: Polymorphisms in GSTT1, GSTM1, NAT1 and NAT2genes and bladder cancer risk in men and women
Variable | NHS | HPFS | ||||
---|---|---|---|---|---|---|
 | Cases (n = 78) | Controls (n = 234) | P-value | Cases (n = 139) | Controls (n = 293) | P-value |
Age at diagnosis (years),1 mean (SD) | 60.6 (9.2) | 60.6 (9.2) | > 0.99 | 68.5 (8.6) | 68.6 (8.6) | 0.87 |
BMI at diagnosis (kg), mean (SD) | 22.0 (9.7) | 23.8 (8.6) | 0.13 | 25.8 (2.8) | 25.5 (3.2) | 0.45 |
Ethnicity/ancestry, n (%) | Â | Â | 0.67 | Â | Â | 0.56 |
   Caucasian | 65 (90.3) | 210 (93.8) |  | 128 (99.2) | 275 (98.9) |  |
   African-American | 2 (2.8) | 3 (1.3) |  | 0 (0.0) | 0 (0.0) |  |
   Asian | 0 (0.0) | 1 (0.45) |  | 0 (0.0) | 0 (0.0) |  |
   Hispanic | 1 (1.4) | 2 (0.89) |  | 0 (0.0) | 0 (0.0) |  |
   Other | 4 (5.6) | 8 (3.6) |  | 1 (0.78) | 3 (1.1) |  |
Packyears at diagnosis2, mean (SD) | 30.2 (22.3) | 27.6 (23.1) | 0.49 | 30.9 (19.8) | 26.9 (19.0) | 0.14 |
Alcohol use at diagnosis (g), mean (SD) | 6.3 (9.3) | 6.1 (10.8) | 0.86 | 16.1 (19.4) | 13.2 (15.2) | 0.12 |
Smoking status at diagnosis, n (%) | Â | Â | 0.12 | Â | Â | 0.81 |
   Never | 22 (29.7) | 72 (31.0) |  | 38 (31.9) | 83 (32.1) |  |
   Former | 37 (50.0) | 127 (54.7) |  | 67 (56.3) | 143 (55.2) |  |
   Current | 15 (20.3) | 33 (14.2) |  | 14 (11.8) | 33 (12.7) |  |