Figure 6From: Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells Burst and xenograft assays. A. Burst assays showing that the E1A-HD2 viruses vCF212 (derived from vCF22: Tcf-E1A, E1B, E2, E4) and vCF192 (derived from vKH1: Tcf-E1A, E1B, E4) have similar burst size to the parental viruses in SW480, Hct116 and Co115 colon cancer cells and HeLa cells. Error bars: SEM, n = 3. B. Growth curves of subcutaneous SW620 xenografts in NMRI nu/nu mice. Mice received 1011 particles of vKH1, vCF192 or buffer control i.v. on day 0. Error bars: SEM, n = 6.Back to article page