Table 3 Association between XRCC1 condon 194 and 399 polymorphisms and NPC risk stratified by gender
From: Polymorphisms of XRCC1 genes and risk of nasopharyngeal carcinoma in the Cantonese population
Genotype | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Cases | Controls | Adjusted ORa (95% CI) | P value | Cases | Controls | Adjusted ORa (95% CI) | P value |
XRCC1 Arg194Trp | ||||||||
   Arg/Arg | 175 | 120 | 1.00 |  | 57 | 115 | 1.00 |  |
   Arg/Trp | 121 | 106 | 0.77(0.54–1.10) | 0.16 | 45 | 111 | 0.78(0.46–1.33) | 0.36 |
   Trp/Trp | 10 | 21 | 0.32(0.14–0.70) | 0.004* | 9 | 22 | 1.11(0.47–2.61) | 0.82 |
XRCC1 Arg399Gln | ||||||||
   Arg/Arg | 177 | 130 | 1.00 |  | 64 | 140 | 1.00 |  |
   Arg/Gln | 114 | 105 | 0.81(0.57–1.15) | 0.24 | 38 | 95 | 0.82(0.47–1.43) | 0.48 |
Gln/Gln | 22 | 15 | 1.04(0.52–2.11) | 0.91 | 10 | 15 | 1.28(0.49–3.36) | 0.62 |