Table 5 Association between exposure categories and progesterone receptor expression
Explanatory Variable | Controls | Cases with tumors expressing PR* in 0 to 25% of cells | Cases with tumors expressing PR* in = order 25 to 100% of cells | ||
|---|---|---|---|---|---|
n | n | OR (95% CI)† | n | OR (95% CI)† | |
OC* use | |||||
Never | 103 | 15 | Referent | 33 | Referent |
Ever | 183 | 31 | 3.2 (1.3 – 8.0) | 64 | 1.1 (0.6 – 1.9) |
HRT* use in post-menopausal women | |||||
Never | 58 | 15 | Referent | 23 | Referent |
Ever | 114 | 22 | 0.8 (0.4 – 1.6) | 41 | 0.9 (0.5 – 1.6) |
Current menstrual status | |||||
Menstruating | 114 | 9 | Referent | 33 | Referent |
Post-menopausal | 172 | 37 | 2.7 (1.2 – 5.8) | 64 | 1.3 (0.8 – 2.1) |
Menstrual status 10 years before reference date | |||||
Menstruating | 158 | 21 | Referent | 62 | Referent |
Post-menopausal | 126 | 23 | 0.5 (0.2 – 1.5) | 35 | 0.5 (0.2 – 1.0) |
Current menstrual status | |||||
Menstruating | 72 | 4 | Referent | 17 | Referent |
Post-menopausal and not using HRT | 58 | 15 | 2.4 (1.2 – 5.8) | 23 | 3.1 (1.1 – 8.6) |
Menstrual status 10 years before reference date | |||||
Menstruating | 83 | 8 | Referent | 27 | Referent |
Post-menopausal and not using HRT | 46 | 10 | 0.3 (0.1 – 2.5) | 13 | 0.8 (0.5 – 1.3) |
Smoking status 10 years before reference date | |||||
Non-smoker | 144 | 29 | Referent | 48 | Referent |
Smoker | 142 | 17 | 0.5 (0.3 – 1.0) | 49 | 1.0 (0.6 – 1.5) |
Body Mass Index on reference date | |||||
< 25 | 156 | 23 | Referent | 45 | Referent |
25 – 30 | 66 | 12 | 1.2 (0.5 – 2.5) | 22 | 1.1 (0.5 – 2.4) |
≥ 30 | 64 | 11 | 1.1 (0.6 – 2.0) | 29 | 1.5 (0.8 – 2.6) |
Number of live births | |||||
None | 58 | 2 | Referent | 16 | Referent |
1 | 28 | 5 | 4.0 (0.7 – 22.3) | 17 | 2.1 (0.9 – 4.9) |
≥ 2 | 200 | 39 | 4.3 (1.0 – 18.8) | 64 | 1.1 (0.6 – 2.2) |