Hormonal exposures and the risk of intracranial meningioma in women: a population-based case-control study

BMC Cancer

Table 2 Association between oral contraceptive use and intracranial meningioma in women

Exposure*	Cases n	Controls n	OR (95% CI)†
Oral contraception (O C)
Never	48	103	Referent
Past	90	176	1.5 (0.8 – 2.7)
Current use on reference date	5	7	2.5 (0.5 – 12.6)
Years of OC use
Never	48	103	Referent
Up to 5 years	49	90	1.5 (0.8 – 3.0)
More than 5 years	46	93	1.4 (0.7 – 2.7)
First OC exposure relative to reference date
Never	48	103	Referent
1–9 years before	7	15	1.6 (0.3 – 7.5)
10 or more years before	88	168	1.5 (0.8 – 2.7)

* Reported exposure before reference date, which for a case and her two matched controls was the date the case had surgery for her meningioma.
† Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable conditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.

ISSN: 1471-2407