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Table 2 Relationship between clinicopathological factors and metastasis in advanced gastric cancer

From: Hyperfibrinogenemia is associated with lymphatic as well as hematogenous metastasis and worse clinical outcome in T2 gastric cancer

  

lymph node metastasis

liver metastasis

peritoneal metastasis

variables

total

negative

positive

P value

negative

positive

P value

negative

positive

P value

age (years)

          

≤59

192

56

136

 

183

9

 

170

22

 

≥60

213

48

165

0.1394

194

19

0.1168

194

19

0.4142

gender

          

male

284

76

208

 

264

20

 

258

26

 

female

121

28

93

0.5345

113

8

>0.9999

106

15

0.3684

tumor location

          

upper

124

31

93

 

117

7

 

107

17

 

middle

152

40

112

 

143

9

 

134

18

 

lower

129

33

96

0.969

117

12

0.4303

123

6

0.0389

differentiation

          

differentiated

180

46

134

 

162

18

 

165

15

 

undifferentiated

225

58

167

>0.9999

215

10

0.0314

199

26

0.3225

lymphatic involvement

          

negative

125

68

57

 

119

6

 

119

6

 

positive

280

36

244

<0.0001

258

22

0.2974

245

35

0.0196

venous involvement

          

negative

195

60

135

 

190

5

 

180

15

 

positive

210

44

166

0.0303

187

23

0.0008

184

26

0.1386

serosal invasion

          

negative

240

91

149

 

226

14

 

235

5

 

positive

165

13

152

<0.0001

151

14

0.3236

129

36

<0.0001

tumor size (cm)

          

≤6

215

80

135

 

202

13

 

206

9

 

>6

190

24

166

<0.0001

175

15

0.5571

158

32

<0.0001

Plasma fibrinogen (mg/dl)

          

≤310

234

76

158

 

226

8

 

216

18

 

≥311

171

28

143

0.0002

151

20

0.0014

148

23

0.067