| TGF-β1 |  | p 27 |  | Cyclin D1 |  | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variables | 0 | 1 | 2 | 3 | p | 0 | 1 | 2 | p | 0 | 1 | p |
Sex | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Female | 13 | 7 | 8 | 8 | 0.68 | 26 | 6 | 4 | 0.10 | 0 | 31 | 0.06 |
Male | 7 | 3 | 11 | 6 | Â | 14 | 11 | 2 | Â | 3 | 18 | Â |
Grade | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Well | 8 | 2 | 5 | 1 | 0.58 | 12 | 3 | 1 | 0.02 | 2 | 13 | 0.42 |
Moderate | 7 | 6 | 10 | 10 | Â | 23 | 9 | 1 | Â | 1 | 25 | Â |
Poor | 5 | 2 | 4 | 3 | Â | 5 | 5 | 4 | Â | 0 | 11 | Â |
Stage | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
I | 4 | 0 | 0 | 0 | 0.05 | 3 | 1 | 0 | 0.97 | 1 | 3 | 0.30 |
II | 11 | 4 | 8 | 0 | Â | 14 | 6 | 3 | Â | 0 | 18 | Â |
III | 0 | 1 | 1 | 1 | Â | 3 | 0 | 0 | Â | 0 | 3 | Â |
IV | 5 | 5 | 10 | 13 | Â | 20 | 10 | 3 | Â | 2 | 25 | Â |
Lymph node m. | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Negative | 10 | 6 | 7 | 4 | 0.34 | 19 | 7 | 1 | 0.34 | 3 | 19 | 0.23 |
Positive | 8 | 3 | 6 | 9 | Â | 15 | 7 | 4 | Â | 0 | 22 | Â |
Perineural inv. | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Negative | 3 | 1 | 3 | 2 | 0.95 | 6 | 1 | 2 | 0.21 | 1 | 7 | 0.47 |
Positive | 16 | 8 | 11 | 9 | Â | 28 | 13 | 3 | Â | 2 | 32 | Â |
Distant met. | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Negative | 15 | 5 | 9 | 1 | <0.01 | 9 | 4 | 0 | 0.51 | 2 | 8 | 0.09 |
Positive | 5 | 5 | 10 | 13 | Â | 31 | 13 | 6 | Â | 1 | 41 | Â |
Blood vessel in . | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Negative | 14 | 6 | 10 | 4 | 0.01 | 23 | 9 | 2 | 0.62 | 3 | 25 | 1 |
Positive | 4 | 3 | 5 | 9 | Â | 13 | 5 | 3 | Â | 1 | 17 | Â |