From: A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes
Toxicity
4 Patients in each dose level (mg
50
75
100
150
Nausea
2/4
-
2/4*
2/2
Vomiting
Dizziness
1/4*
1/4
Fatigue
3/4
Flushes
Headache
Edema
Palpitations