Figure 4
From: Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies
Nuclear translocation of p65/RELA in progressing lung neoplasia. Photomicrographs of normal bronchial epithelium (A, B), moderate dysplasia (C, D), or squamous cell carcinoma (E, F) at low (A, C and E) or high (B, D and F) magnification. Staining is diffusely cytoplasmic in normal bronchial epithelium. Nuclear translocation of p65/RELA, rarely detected in normal bronchial epithelium, is present in an increased percentage of moderate to severe dysplasias and squamous cell carcinoma (arrows, D and F).