Figure 4

Intravesical PstS1 immunotherapy in nonsensitized and PstS1-sensitized mice. Ten days before inoculation of MB-49 tumor cells mice were s.c. sensitized by injection of empty L-particles (A/B) or L-particle loaded with PstS1 (C). On days 1, 8, 15 and 22 after tumor challenge, mice were treated by intravesical instillation of PstS1 (A/C) or PBS (B). Mice which received s.c. PBS and intravesical PBS served as control. Survival of mice was analyzed by Kaplan-Meier curve and log rank test.