Figure 6

RUNX1-CBFA2T1 siRNAs induce senescence in Kasumi-1 cellsA. Senescence-associated β-galactosidase stained cells. Kasumi-1 cells were electroporated with siRNAs at days 0 and 4, and were examined at day 8 for senescence by staining for senescence-associated β-galactosidase. B. Quantification of cellular senescence. Cells were treated as above, and the ratio of β-galactosidase positive cells was examined by counting. Error bars represent the standard deviations of single-blinded counts performed by three different experimentators. †, p < 0.01 according to Student's t-test