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Table 3 b3a2 association with HLA Class I and II in leukemia patients and healthy donors with statistical analysis

From: Association of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)

HLA

ALLELE

LEUKEMIA PATIENTS*

HEALTHY DONORS*

RELATIVE RISK

CHI-SQUARE

BINDING SCORE

A

25

4

4

3.74

3.94

 

A

68

7

107

0.21

17.80

8

B

14

5

99

0.16

19.57

5

B

15

5

60

0.28

8.04

 

B

37

5

2

9.22

10.27

 

B

49

6

2

11.12

13.50

 

B

51

13

19

2.57

6.99

4

B

53

5

3

6.14

7.91

3

B

56

3

2

5.48

4.34

 

B

60

8

0

60080000.00

29.13

 

B

62

6

0

45060000.00

21.80

8

DQB1

0303

4

30

0.33

4.62

 

DQB1

0609

3

0

16110000.00

7.78

 

DRB1

0405

4

2

5.25

4.51

 

DRB1

0701

21

99

0.50

7.72

 

DRB1

0802

3

1

7.84

4.43

 

DRB1

0901

4

1

10.51

6.78

 

DRB1

1001

4

2

5.25

4.51

 

DRB1

1503

3

1

7.84

4.43

 
  1. *Figures shown are the gene frequencies. For a significance level of = 0.05 needed to reject the null hypothesis, the chi square statistic must be > 3.84