Table 5 Tags most significantly overexpressed in KS compared with normal skin. For comparison tag numbers for each group were normalized to 50,000
From: Gene expression profile of AIDS-related Kaposi's sarcoma
No. | Tag | ID | KS | NS |
|---|---|---|---|---|
1 | GACCGCAGGA | Collagen, type IV, α1 (basement membrane collagen) | 117 | 1 |
2 | GTGCGCTGAG | MHC, class I C | 93 | 1 |
3 | CGTGGGTGGG | Heme oxygenase (decyling) 1 | 171 | 5 |
4 | CTCTAAGAAG | Complement component 1q subcomponent α peptide | 40 | 1 |
5 | GAGAGTGTCT | Tissue inhibitor of metalloproteinase (TIMP) | 31 | 1 |
6 | GCGGTTGTGG | Lysosomal-associated multispanning membrane protein 5 | 28 | 1 |
7 | CGGGGTGGCC | Cartilage oligomeric matrix protein | 28 | 0 |
8 | GCAAGAAAGT | Hemoglobin β | 24 | 0 |
9 | ACCGCCGTGG | Cytochrome b-245, α polypeptide | 22 | 1 |
10 | CCGGGTGATG | ATX1 (antioxidant protein1) | 22 | 1 |
11 | GCTGCGGTCC | H2A histone family member | 19 | 1 |
12 | GTGTTAACCA | Ribosomal protein L15 | 19 | 1 |
13 | ACCATTCTGC | Interferon induced transmembrane protein 2 (1-8D) | 19 | 1 |
14 | GGCTCCCACT | Heat shock 90 kD protein1, beta | 18 | 0 |
15 | CGGGATTCCT | Phospholipid transfer protein | 18 | 1 |
16 | GCTGGTGCCT | Thy-1 cell surface antigen | 17 | 1 |
17 | TACAGTATGT | Glutamate-ammonia ligase, glutamine synthase | 17 | 1 |
18 | GAGCAGCGCC | S100 calcium binding protein A7 (Psoriasin)* | 101 | 8 |
19 | ACTTTAGATG | Collagen type VI α3 | 33 | 3 |
20 | GTGGCCACGG | S100 calcium binding protein A9 (Calgranulin B) | 96 | 8 |
21 | GCCCCTCCGG | 16,7 Kd protein (function unknown) | 16 | 1 |
22 | AGTAGCCGTG | No reliable matches | 16 | 1 |
23 | ACAGGGTGAC | Endothelial differentiation-related factor 1 | 15 | 1 |
24 | TGGAGAAGAG | Thioredoxin interacting protein | 15 | 1 |
25 | TGTCATCACA | Lysyl oxidase-like 2 (senescence and cell adhesion) | 15 | 1 |
26 | CTGTTAGTGT | Malate dehydrogenase 1, NAD (soluble) | 15 | 1 |
27 | TCACCTTAGG | Integral membrane protein 2β | 15 | 0 |
28 | ACAAGTACTG | Cadherin 5 type 2, VE-cadherin * (expressed specially in endothelial cells) | 15 | 0 |
29 | GATCAATCAG | Small inducible cytokine subfamily A member 18* | 14 | 0 |
30 | CAGCTGTCCC | Keratin 16 (expressed by hyperproliferative cells) * | 12 | 0 |
31 | GGCTGGTCTG | Hypothetical protein MGC4677 | 28 | 3 |
32 | ATCTTGTTAC | Fibronectin (involved in cell adhesion and migration) | 13 | 1 |
33 | GCCGGGTGGG | Basigin (Ok blood group) | 13 | 1 |
34 | TCGTAACGAG | Hypothetical protein FLJI4987 | 13 | 1 |
35 | TGGGTGAGCC | Cathepsin B (lysosomal cys protease) | 78 | 8 |
36 | TGCATCTGGT | Heat shock 70 KD protein 5 | 39 | 4 |
37 | GTGCTGGACC | Proteasome activator subunit 2 | 13 | 1 |
38 | GATCAGGCCA | Collagen, type III, α1 (blood vessel collagen) | 105 | 11 |
39 | CTGGGTGCCT | Immunoglobulin heavy constant gamma 3 (G3 m Marker) | 37 | 4 |
40 | CCAGTGGCCC | Ribosomal protein S9 | 46 | 5 |
41 | CTAGCCTCAC | Actin, gamma 1 | 25 | 3 |
42 | CTCATAGCAG | Tumor protein, translationally controlled 1 | 24 | 3 |
43 | GCGGGGTACC | pM5 protein | 23 | 3 |
44 | CTCCCCCAAG | Homosapiens SNC73 protein | 23 | 3 |
45 | TCAGACGCAG | Prothymosin α | 56 | 6 |
46 | ACCTGTATCC | Interferon induced transmembrane protein 3 (1-8U) | 90 | 10 |
47 | ACATAGACCG | Serine (or cysteine) proteinase inhibitor clade F, member 1 | 12 | 1 |
48 | GCACAACAAG | Uncharacterized hypothalamus protein HTMP | 12 | 1 |
49 | TGCTGCCTGT | Bone marrow stromal cell antigen 21 | 22 | 3 |
50 | CATCACGGAT | Interleukin 1 receptor, type 1 * | 22 | 3 |
51 | ATTTAGCAAG | Fatty acid binding protein 4, adipocyte * | 33 | 4 |
52 | TCCCCGTACC | Lamin A/C | 11 | 1 |
53 | ACAAGGTGCC | No reliable matches | 11 | 1 |
54 | CTTGACATAC | Dual specificity phosphatase 1* | 11 | 1 |
55 | CCCGGGAGCG | PDZ and LIM domain1 (elfin) * | 11 | 1 |
56 | TAGCTGCTGG | Splicing factor, arginine/serine-rich 11 * | 11 | 1 |
57 | GTGCTGGTGC | Potassium channel subfamily K, member 6 / angiopoietin like 4 | 11 | 0 |
58 | GTTAACGTCC | Ribosomal protein L44 | 21 | 3 |
59 | CCAGGGGAGA | Interferon, alpha-inducible protein 27 | 31 | 4 |
60 | TGGCCCCACC | Pyruvate kinase, muscle | 10 | 1 |
61 | GGAAGCTAAG | Osteoblast specific factor 2 (fascilin I-like) * | 10 | 1 |
62 | TAGTTGATGG | Galectin 1 * | 10 | 1 |
63 | CTCCATTGCC | Sialoadhesin /CD169* | 7 | 0 |
64 | CCCTGTTCAG | Tie 1* | 13 | 2 |