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Figure 1 | BMC Cancer

Figure 1

From: Up-regulated MicroRNA-181a induces carcinogenesis in Hepatitis B virus-related hepatocellular carcinoma by targeting E2F5

Figure 1

HBV up-regulated the expression of miR-181a by increasing its promoter activity. (A) Relative expression of miR-181a in HepG2 and HepG2.2.15. (B) Relative expression of miR-181a in Ad-HBV or Ad-GFP infected HepG2 cells. miRNA abundance was normalized to U6 RNA. (C) Dual luciferase reporter analysis was performed to analyze miR-181a promoter activity in HepG2.2.15 and HepG2 cells. (D) miR-181a promoter activity in HepG2 cells with Ad-GFP or Ad-HBV infection. *P < 0.05, **P<0.01.

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