Table 1 Demographic and clinical characteristics
From: Radiation therapy of anal canal cancer: from conformal therapy to volumetric modulated arc therapy
CRT | RA | |||
|---|---|---|---|---|
n | % | n | % | |
Total no of patients | 28 | - | 36 | - |
Age, years | ||||
Median | 59 [41–80] | - | 65 [44–84] | - |
Sex | ||||
Male | 9 | 32.1 | 7 | 19.4 |
Female | 18 | 64.3 | 29 | 80.6 |
HIV status | ||||
Positive | 3 | 10.7 | 3 | 8.3 |
Negative | 24 | 85.7 | 33 | 91.7 |
HPV status | ||||
Positive | 2 | 7.1 | 1 | 2.8 |
Negative | 25 | 92.8 | 35 | 97.2 |
T stage | ||||
Tx | 0 | 0 | 2 | 5.6 |
T1 | 1 | 3.6 | 1 | 2.8 |
T2 | 18 | 64.3 | 21 | 58.3 |
T3 | 6 | 21.4 | 9 | 25.0 |
T4 | 3 | 10.7 | 3 | 8.3 |
N stage | ||||
Nx | 1 | 3.6 | 0 | 0 |
N0 | 12 | 42.9 | 23 | 63.9 |
N1 | 12 | 42.9 | 6 | 16.7 |
N2 | 1 | 3.6 | 2 | 5.6 |
N3 | 2 | 7.1 | 5 | 13.9 |
M stage | ||||
M0 | 28 | 100 | 35 | 97.2 |
M1 | 0 | 0 | 1 | 2.8 |
Stage | ||||
X | 1 | 3.6 | 2 | 5.6 |
I | 1 | 3.6 | 1 | 2.8 |
II | 10 | 35.7 | 19 | 52.8 |
III | 16 | 57.1 | 13 | 36.1 |
IV | 0 | 0 | 1 | 2.8 |
Chemotherapy | ||||
FU/MMC | 11 | 39.3 | 29 | 80.5 |
FU/CDDP | 16 | 57.1 | 2 | 5.5 |
FU | 1 | 3.6 | 0 | 0 |
None | 0 | 0 | 5 | 13.9 |
Radiation therapy (33 fractions) | ||||
Prescription (Gy) | 45/59.4 | 49.4/59.4 | ||
Duration median (days) | 49 | 51.0 | ||
RT break >3 days | 6 | 21 | 6 | 17 |
Median break (days) | 10 | - | 7.5 | - |