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Table 3 Frequency, site of first recurrence and first salvage treatment modality for locoregional recurrence

From: Comparison of concurrent chemoradiotherapy versus neoadjuvant chemotherapy followed by radiation in patients with advanced nasopharyngeal carcinoma in endemic area: experience of 128 consecutive cases with 5 year follow-up

 

CCRT group (n = 90)

 

NACT group (n = 38)

 
 

No.

%

No.

%

First failure site

    

 Locoregional

12

13.3

9

23.7

 Distant

14a

15.6

8

21.1

  Lung

4

 

4

 

  Bone

6

 

2

 

  Liver

5

 

1

 

  Others

2b

 

1c

 

First treatment modality for locoregional failure

    

 Surgery

1

8.3

-

 

 Re-irradiation

1

8.3

6

66.7

 Re-CCRT

5

41.7

3

33.3

 Chemotherapy

5

41.7

-

 
  1. aOne patient had bone and lung metastases concurrently and the other one had bone, liver and lung metastases simultaneously bone patient developed mediastinal lymph node metastases and the other one developed para-aortic lymph node metastases cthe subject developed axillary lymph node metastases.