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Table 4 Descriptive characteristics of ovarian cancer cases and controls, the African American Cancer Epidemiology Study (AACES), 2010-14†

From: A multi-center population-based case–control study of ovarian cancer in African-American women: the African American Cancer Epidemiology Study (AACES)

Variable

Cases (N = 371)

Controls (N = 622)

    
 

N (%)

N (%)

OR*

(95% CI)

OR**

(95% CI)

Age group (years)

      

20-39

23 (6.2)

77 (12.4)

    

40-49

61 (16.4)

115 (18.5)

    

50-59

131 (35.3)

219 (35.2)

    

60-69

97 (26.1)

157 (25.2)

    

70-79

59 (15.9)

54 (8.7)

    

Age at menarche (years)

      

<12

83 (22.4)

167 (26.8)

1.00

Referent)

1.00

Referent

12-13

186 (50.1)

300 (48.2)

1.22

(0.88-1.69)

1.30

(0.93-1.80)

13+

102 (27.5)

155 (24.9)

1.27

(0.88-1.84)

1.35

(0.93-1.97)

Parity

      

0

67 (18.1)

83 (13.3)

1.00

Referent

1.00

Referent

1-2

159 (42.9)

284 (45.7)

0.66

(0.45-0.97)

0.69

(0.47-1.01)

>3

145 (39.1)

255 (41.0)

0.61

(0.41-0.90)

0.61

(0.41-0.91)

Tubal ligation

      

No

235 (63.5)

375 (60.4)

1.00

Referent

1.00

Referent

Yes

135 (36.5)

246 (39.6)

0.84

(0.64-1.10)

0.96

(0.71-1.28)

Missing

1

1

    

Oral contraceptive use (months)

      

Never to <3

129 (34.8)

145 (23.3)

1.00

Referent

1.00

Referent

3- < 36

102 (27.5)

192 (30.9)

0.64

(0.46-0.91)

0.66

(0.47-0.93)

36 < -60

31 (8.4)

67 (10.8)

0.54

(0.33-0.89)

0.55

(0.33-0.90)

60+

109 (29.4)

218 (35.0)

0.58

(0.42-0.82)

0.58

(0.41-0.82)

Menopausal status

      

Post-menopausal

266 (72.3)

410 (66.2)

1.00

Referent

1.00

Referent

Pre-menopausal

102 (27.7)

209 (33.8)

1.21

(0.78-1.89)

1.23

(0.78-1.92)

Missing

3

3

    

Hysterectomy

      

No

279 (75.2)

495 (79.6)

1.00

Referent

1.00

Referent

Yes

92 (24.8)

127 (20.4)

1.12

(0.82-1.54)

1.12

(0.82-1.55)

Use of hormone replacement therapy among women over age > =50

      

No

216 (75.8)

341 (79.7)

1.00

Referent

1.00

Referent

Yes

69 (24.2)

87 (20.3)

1.17

(0.81-1.69)

1.25

(0.86-1.82)

Missing

2

2

    

First degree relative with ovarian cancer

      

No

340 (94.7)

578 (96.8)

1.00

Referent

1.00

Referent

Yes

19 (5.3)

19 (3.2)

1.57

(0.82-3.03)

1.60

(0.82-3.12)

Missing

12

25

    

First degree relative with breast cancer

      

No

281 (77.6)

506 (84.2)

1.00

Referent

1.00

Referent

Yes

81 (22.4)

95 (15.8)

1.46

(1.04-2.04)

1.50

(1.07-2.11)

Missing

9

21

    

First degree relative with ovarian and/or breast cancer

      

No

267 (73.8)

491 (81.7)

1.00

Referent

1.00

Referent

Yes

95 (26.2)

110 (18.3)

1.50

(1.09-2.06)

1.53

(1.11-2.11)

Missing

9

21

    

Body mass index 1 year before diagnosis (kg/m 2 )

      

<24.9

54 (14.6)

119 (19.2)

1.00

Referent

1.00

Referent

25–29.9

95 (25.7)

157 (25.3)

1.24

(0.82-1.88)

1.31

(0.86-1.99)

30–34.9

107 (29.0)

157 (25.3)

1.49

(0.99-2.24)

1.50

(0.99-2.27)

> = 35

113 (30.6)

188 (30.3)

1.29

(0.86-1.92)

1.27

(0.85-1.91)

Missing

2

1

    

Education

      

High school or less

173 (46.6)

223 (35.9)

1.00

Referent

1.00

Referent

Some post-high school training

115 (31.0)

227 (36.6)

0.69

(0.51-0.93)

0.69

(0.51-0.95)

College or graduate degree

83 (22.4)

171 (27.5)

0.66

(0.48-0.93)

0.66

(0.46-0.95)

Missing

 

1

    

Annual Income

      

< $10,000

85 (23.4)

130 (21.2)

1.00

Referent

1.00

Referent

$10,000 - < $25,000

98 (26.9)

145 (23.6)

1.00

(0.68-1.46)

1.04

(0.71-1.53)

$25,000 - < $50,000

88 (24.2)

131 (21.3)

1.04

(0.71-1.54)

1.08

(0.72-1.60)

$50,000 - < $75.000

48 (13.2)

103 (16.8)

0.72

(0.46-1.12)

0.75

(0.48-1.19)

≥$75,000

45 (12.4)

105 (17.1)

0.66

(0.42-1.04)

0.73

(0.46-1.17)

Missing

7

8

    

Private Physician

      

No

104 (29.1)

158 (26.2)

1.00

Referent

1.00

Referent

Yes

253 (70.9)

445 (73.8)

0.77

(0.57-1.03)

0.77

(0.57-1.05)

Missing

14

19

    

Current Insurance

      

None

41 (11.1)

76 (12.3)

1.00

Referent

1.00

Referent

Medicaid

97 (26.1)

124 (20.0)

1.37

(0.86-2.20)

1.38

(0.85-2.22)

Medicare

96 (25.9)

128 (20.6)

1.04

(0.63-1.74)

1.03

(0.61-1.72)

Other Insurance

137 (36.9)

292 (47.1)

0.84

(0.54-1.29)

0.86

(0.56-1.34)

Missing

0

2

    

Ever smoked

      

Current/Former

163 (43.9)

259 (41.6)

1.00

Referent

1.00

Referent

Never

208 (56.1)

363 (58.4)

0.97

(0.75-1.27)

1.00

(0.76-1.30)

  1. †Forty-nine patients (32 cases and 17 controls) were excluded from this table due to missing data for either parity or months of oral contraceptive use.
  2. OR = Odds Ratio, CI = Confidence Interval.
  3. *Age adjusted(ORs).
  4. **Multivariable adjusted (ORs) adjusted for age, months of oral contraceptive use, and parity.