Table 1 Patient’s characteristic
From: Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST)
ID | Sex | Array | RNAseq | Age | Site | Disease status at diagnosis | KIT/PDGFRA/SDH mutational status |
|---|---|---|---|---|---|---|---|
GIST_133 | M | X | X | 57 | Duodenum | Localized | WT |
GIST_127 | F | X | X | 63 | Ileum | Localized | WT |
GIST_07 | F | X | X | 27 | Stomach | Metastatic | SDHA exon 9 p.S384X |
GIST_10 | M | X | X | 29 | Stomach | Metastatic | SDHA exon 2 p.R31X; |
SDHA exon 13 p.R589W | |||||||
GIST_188 | F | X | 57 | Duodenum | Metastatic | KIT exon 11 p.N564-L576 del + KIT exon 17 p.N822K | |
GIST_174 | M | X | 59 | Stomach | Metastatic | KIT exon 11 p.N564_L576 del + KIT exon 17 p.N822K | |
GIST_131 | M | X | X | 58 | Ileum | Localized | KIT exon 11 p.V569_Y578 del |
GIST_11 | M | X | X | 65 | Stomach | Localized | KIT exon 11 p.557-558 del |
GIST_134 | F | X | X | 65 | Stomach | Localized | KIT exon p.V559D |
GIST_124 | M | X | X | 70 | Stomach | Localized | KIT exon 11 p.1765-1766 ins |
GIST_150 | F | X | 55 | Stomach | Localized | KIT exon 11 p.P551_E554 del | |
GIST_165 | M | X | 50 | Stomach | Localized | PDGFRA exon 18 p.D842V | |
GIST_136 | M | X | X | 76 | Stomach | Localized | PDGFRA exon 18 p.D842V |
GIST_140 | F | X | 45 | Stomach | Localized | PDGFRA exon 18 p.D842V | |
GIST_141 | M | X | 68 | Stomach | Localized | PDGFRA exon 18 p.D842V | |
GIST_138 | F | X | 75 | Stomach | Localized | PDGFRA exon 18 p.D842V | |
GIST_02 | F | X | 85 | Stomach | Localized | KIT exon 11 p.V560D | |
GIST_04 | M | X | 79 | Stomach | Localized | KIT exon 9 p.AY502-503 ins | |
GIST_05 | M | X | 68 | Stomach | Localized | PDGFRA exon 12 p.SPDGHE566-571RIQ | |
GIST_08 | M | X | 62 | Stomach | Localized | KIT exon 11 p.V559D | |
GIST_09 | M | X | 54 | Stomach | Localized | KIT exon 11 TLQPYDHKWEEFP 574–585 ins at P585 | |
GIST_12 | F | X | 66 | Stomach | Localized | PDGFRA exon 14 p.K646E | |
GIST_13 | M | X | 46 | Small intestine | Localized | KIT exon 11 p.V559D | |
GIST_14 | M | X | 56 | Stomach | Localized | KIT exon 11 p.WK557-558del | |
GIST_15 | F | X | 64 | Stomach | Localized | PDGFRA exon 18 DIMH p.842-845 DIMH del | |
GIST_16 | F | X | 62 | Stomach | Localized | KIT exon 11 p.L576P | |
GIST_20 | M | X | 38 | Small intestine | Metastatic | KIT exon 11 del MYEQW552-557 Z + KIT exon 18 A829P | |
GIST_22 | F | X | 76 | Stomach | NA | PDGFRA exon 18 p.D842V | |
GIST_23 | F | X | 47 | Stomach | NA | KIT exon 11 p.V559D | |
GIST_24 | F | X | 18 | Stomach | Metastatic | SDHA exon 8 p.L349R fs*11 | |
GIST_26 | M | X | 49 | Stomach | Localized | PDGFRA exon 12 p.V561D | |
GIST_121 | M | X | 71 | Stomach | Localized | KIT exon 11 p.V559D | |
GIST_125 | F | X | 48 | Stomach | Localized | KIT exon 11 p.W557R | |
GIST_129 | M | X | 59 | Stomach | Localized | KIT exon11 p.Y553_V559 delins L | |
GIST_130 | F | X | 79 | Stomach | Localized | KIT exon 9 p.A502-Y503 ins | |
GIST_135 | F | X | 61 | Stomach | Localized | KIT exon 11 p.W557-E561 del |