Table 2 Patients characteristics
Patients number | 82 |
|---|---|
Mean age (range) y | 68 (40–87) |
Sex (M:F) | 62:21 |
Primary | Â |
  Colon | 58 (71%) |
  Rectum | 24 (29%) |
TNM Primary Classification | Â |
  T1 | 2 (3%) |
  T2 | 17 (21) |
  T3 | 57 (70%) |
  T4 | 6(7%) |
  N0 | 39 (48%) |
  N1-2 | 43 (52%) |
  M1 | 23 (28%) |
   Only liver | 42 (51%) |
   Only lung | 40 (49%) |
Timing of liver metastases | Â |
  Synchronous | 23 (28%) |
  Metachronous | 59 (82%) |
   DFI ≤ 12 months | 14 (24%) |
   DFI > 12 months | 45 (76%) |
Previous local treatments | Â |
  Surgery | 33 (40%) |
  RFA or other | 7 (9%) |
Systemic treatments | Â |
  Pre-SBRT chemotherapy | 78 (95%) |
  Post-SBRT chemotherapy | 20 (24%) |
Time of SBRT since diagnosis | Â |
  <12 mo | 7 (8%) |
  >12 mo | 75 (92%) |
No. of prior systemic treatment regimens | Â |
  0 | 4 (5%) |
  1 | 15 (18%) |
  2 | 25 (30%) |
  3 | 23 (28%) |
  >4 | 15 (19%) |
Presence of stable extrahepatic and pulmonary metastatic disease at diagnosis | Â |
  Yes | 27 (33%) |
  No | 55 (67%) |
Number of lesions treated | 112 |
Number of lesions for patients | Tot Liver Lung |
  1 | 61 (74%) 35 (83%) 26 (65%) |
  2 | 13 (16%) 4 (10%) 9 (23%) |
  3 | 8 (10%) 3 ( 7%) 5 (12%) |
  Mean volume (range) [cm3] |  |
  CTV | 20.3 ± 24.09 (1.0-140.3) |
  PTV | 60.60 ± 42.16 (6.3-980.13) |