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Table 4 Identification of genes differentially expressed by SSH in PR

From: Correlation between ERK1 and STAT3 expression and chemoresistance in patients with conventional osteosarcoma

Gene title

Gene symbol

Chromosomal location

Actin, alpha 1, skeletal muscle

ACTA1

chr1q42.13-q42.2

Actin, beta

ACTB

chr7p15-p12

Actin, gamma 1

ACTG1

chr17q25

Actinin, alpha 1

ACTN1

chr14q24.1-q24.2|14q24|14q22-q24

ADAM metallopeptidase with thrombospondin type 1 motif, 20

ADAMTS20

chr12q12

v-akt murine thymoma viral oncogene homolog 2

AKT2

chr19q13.1-q13.2

Ankyrin repeat domain 11

ANKRD11

chr16q24.3

Annexin A2

ANXA2

chr15q21-q22

AT rich interactive domain 4B (RBP1-like)

ARID4B

chr1q42.1-q43

Actin-related protein 2/3 complex, subunit 2, 34 kDa

ARPC2

chr2q36.1

ATPase family, AAA domain containing 3A

ATAD3A

chr1p36.33

ATP synthase, H + transporting, mitochondrial F0 complex, subunit E///major facilitator superfamily domain containing 7

ATP5I///MFSD7

chr4p16.3

Bromo adjacent homology domain containing 1

BAHD1

chr15q15.1

Breast carcinoma amplified sequence 3

BCAS3

chr17q23

Branched chain aminotransferase 2, mitochondrial

BCAT2

chr19q13

Chromosome 14 open reading frame 112

C14orf112

chr14q24.2

Chromosome 14 open reading frame 2

C14orf2

chr14q32.33

Chromosome 20 open reading frame 194

C20orf194

chr20p13

Cell adhesion molecule 1

CADM1

chr11q23.2

Coiled-coil domain containing 28B

CCDC28B

chr1p35.1

Chaperonin containing TCP1, subunit 8 (theta)

CCT8

chr21q22.11

Cell division cycle 34 homolog (S. cerevisiae)

CDC34

chr19p13.3

Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

CDKN2C

chr1p32

Carbohydrate (chondroitin 4) sulfotransferase 11

CHST11

chr12q

Creatine kinase, brain

CKB

chr14q32

CDC28 protein kinase regulatory subunit 1B

CKS1B

chr1q21.2

CLPTM1-like

CLPTM1L

chr5pter-p15.3

Cornifelin

CNFN

chr19q13.2

Collagen, type V, alpha 1

COL5A1

chr9q34.2-q34.3

Catechol-O-methyltransferase

COMT

chr22q11.21-q11.23|22q11.21

Cytochrome c oxidase subunit VIa polypeptide 1

COX6A1

chr12q24.2|12q24.2

Cytokine receptor-like factor 1

CRLF1

chr19p12

Chondroitin sulfate glucuronyltransferase

CSGlcA-T

chr7q36.1

Casein kinase 2, alpha prime polypeptide

CSNK2A2

chr16q21

cutA divalent cation tolerance homolog (E. coli)

CUTA

chr6pter-p21.31

dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)

DCI

chr16p13.3

Dicarbonyl/L-xylulose reductase

DCXR

chr17q25.3

DEAD (Asp-Glu-Ala-As) box polypeptide 19A

DDX19A

chr16q22.1

DEAD (Asp-Glu-Ala-As) box polypeptide 19B///DEAD (Asp-Glu-Ala-As) box polypeptide 19A

DDX19A///DDX19B

chr16q22.1

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39

DDX39

chr19p13.12

Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)

EEF1D

chr8q24.3

Eukaryotic elongation factor-2 kinase

EEF2K

chr16p12.1

Eukaryotic translation initiation factor 3, subunit H

EIF3H

chr8q24.11

Eukaryotic translation initiation factor 4 gamma, 3

EIF4G3

chr1p36.12

Fas apoptotic inhibitory molecule 3

FAIM3

chr1q32.1

FK506 binding protein 7

FKBP7

chr2q31.2

Kappa-actin

FKSG30

chr2q21.1

Flavin containing monooxygenase 5

FMO5

chr1q21.1

Fibronectin 1

FN1

chr2q34

FERM domain containing 5

FRMD5

chr15q15.3

Golgi SNAP receptor complex member 2

GOSR2

chr17q21

Glypican 1

GPC1

chr2q35-q37

G protein-coupled receptor 108

GPR108

chr19p13.3

Ribosomal protein L23a///similar to ribosomal protein L23A///ribosomal protein L23a-like

hCG_16001///hCG_2001000///RPL23A

chr17q11///chr17q23.2///chr3q26.1

v-Ha-ras Harvey rat sarcoma viral oncogene homolog

HRAS

chr11p15.5

Heparan sulfate proteoglycan 2

HSPG2

chr1p36.1-p34

Insulin-like growth factor 2 mRNA binding protein 3

IGF2BP3

chr7p11

Inositol(myo)-1(or 4)-monophosphatase 2

IMPA2

chr18p11.2

Integrator complex subunit 1

INTS1

chr7p22.3

Importin 11

IPO11

chr5q12.1

Jumonji domain containing 2C

JMJD2C

chr9p24.1

KIAA0999 protein

KIAA0999

chr11q23.3

Laminin, alpha 4

LAMA4

chr6q21

Lectin, galactoside-binding, soluble, 1 (galectin 1)

LGALS1

chr22q13.1

Lamin A/C

LMNA

chr1q21.2-q21.3

Ribosomal protein S16///similar to 40S ribosomal protein S16

LOC441876///RPS16

chr19q13.1///chr1p36.21

Leucine-rich repeat containing 28

LRRC28

chr15q26.3

Microtubule-associated protein 1S

MAP1S

chr19p13.11

Mitogen-activated protein kinase 3

MAPK3 (ERK1)

chr16p11.2

Major facilitator superfamily domain containing 5

MFSD5

chr12q13.13

Mitochondrial ribosomal protein S7

MRPS7

chr17q25

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9 kDa

NDUFA4

chr7p21.3

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20 kDa (NADH-coenzyme Q reductase)

NDUFS7

chr19p13.3

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa

NDUFV1

chr11q13

Nuclear factor I/C (CCAAT-binding transcription factor)

NFIC

chr19p13.3

NOL1/NOP2/Sun domain family, member 5

NSUN5

chr7q11.23

NOL1/NOP2/Sun domain family, member 5B

NSUN5B

chr7q11.23

NOL1/NOP2/Sun domain family, member 5C

NSUN5C

chr7q11.23

Nucleoporin 214 kDa

NUP214

chr9q34.1

Nucleoporin 85 kDa

NUP85

chr17q25.1

PDZ domain containing 2

PDZD2

chr5p13.3

Periplakin

PPL

chr16p13.3

Protein phosphatase 1, regulatory (inhibitor) subunit 12B

PPP1R12B

chr1q32.1

Protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform

PPP2R1A

chr19q13.33

Protein kinase C substrate 80 K-H

PRKCSH

chr19p13.2

Protein arginine methyltransferase 2

PRMT2

chr21q22.3

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))

RALY

chr20q11.21-q11.23

RNA binding motif protein 4

RBM4

chr11q13

RNA binding motif protein 4B

RBM4B

chr11q13

RNA binding motif protein 8A

RBM8A

chr1q12

Ribosomal protein L13

RPL13

chr16q24.3|17p11.2

Ribosomal protein L13a

RPL13A

chr19q13.3

Ribosomal protein L19

RPL19

chr17q11.2-q12

Ribosomal protein L23a

RPL23A

chr17q11

Ribosomal protein L31

RPL31

chr2q11.2

Ribosomal protein, large, P1

RPLP1

chr15q22

Ribosomal protein S12

RPS12

chr6q23.2

Ribosomal protein S14

RPS14

chr5q31-q33

Ribosomal protein S17

RPS17

chr15q

Ribosomal protein S21

RPS21

chr20q13.3

Ribosomal protein S27 (metallopanstimulin 1)

RPS27

chr1q21

Ribosomal protein S6

RPS6

chr9p21

RNA pseudouridylate synthase domain containing 4

RPUSD4

chr11q24.2

Ribosomal RNA processing 1 homolog B (S. cerevisiae)

RRP1B

chr21q22.3

Retinoid X receptor, alpha

RXRA

chr9q34.3

Synaptonemal complex protein SC65

SC65

chr17q21.2

Splicing factor, arginine/serine-rich 3

SFRS3

chr6p21

Serine hydroxymethyltransferase 2 (mitochondrial)

SHMT2

chr12q12-q14

SIVA1, apoptosis-inducing factor

SIVA1

chr14q32.33

SIVA1, apoptosis-inducing factor

SIVA1

chr14q32.33

Solute carrier family 16, member 8 (monocarboxylic acid transporter 3)

SLC16A8

chr22q12.3-q13.2

Solute carrier family 20 (phosphate transporter), member 2

SLC20A2

chr8p12-p11

Small nuclear ribonucleoprotein D3 polypeptide 18 kDa

SNRPD3

chr22q11.23

Signal transducer and activator of transcription 3 (acute-phase response factor)

STAT3

chr17q21.31

Serine/threonine kinase 24 (STE20 homolog, yeast)

STK24

chr13q31.2-q32.3

T-cell, immune regulator 1, ATPase, H + transporting, lysosomal V0 subunit A3

TCIRG1

chr11q13.2

Testis-specific kinase 1

TESK1

chr9p13

Thymosin, beta 10

TMSB10

chr2p11.2

Transportin 3

TNPO3

chr7q32.1

Tetraspanin 9

TSPAN9

chr12p13.33-p13.32

Ubiquitin A-52 residue ribosomal protein fusion product 1

UBA52

chr19p13.1-p12

Vacuolar protein sorting 28 homolog (S. cerevisiae)

VPS28

chr8q24.3

Williams-Beuren syndrome chromosome region 16

WBSCR16

chr7q11.23

WW domain containing oxidoreductase

WWOX

chr16q23.3-q24.1

X antigen family, member 1D///X antigen family, member 1C///X antigen family, member 1E///X antigen family, member 1///X antigen family, member 1B

XAGE1///XAGE1B///XAGE1C///XAGE1D///XAGE1E

chrXp11.22

Zinc finger protein 449

ZNF449

chrXq26.3