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Table 1 Family history of cancer and gastroesophageal disorders by demographic and lifestyle characteristics among control subjects

From: Family history of cancer and gastroesophageal disorders and risk of esophageal and gastric adenocarcinomas: a case–control study

 

Family history of any cancer

Family history of gastroesophageal disorders

N (row percent)

No

Yes

P a

No

Yes

P a

Age

  

0.005

  

<0.001

 ≤49

161 (58.8%)

113 (41.2%)

 

169 (61.7%)

105 (38.3%)

 

 50-59

174 (52.6%)

157 (47.4%)

 

217 (65.8%)

113 (34.2%)

 

 60-69

215 (48.3%)

230 (51.7%)

 

337 (76.8%)

102 (23.2%)

 

 ≥70

118 (47.8%)

129 (52.2%)

 

196 (79.7%)

50 (20.3%)

 

Gender

  

0.70

  

0.003

 Male

499 (51.8%)

464 (48.2%)

 

703 (73.6%)

252 (26.4%)

 

 Female

169 (50.6%)

165 (49.4%)

 

216 (64.7%)

118 (35.3%)

 

Race

  

<0.001

  

0.19

 Non-Hispanic white

382 (46.8%)

434 (53.2%)

 

590 (72.6%)

223 (27.4%)

 

 African American

44 (51.2%)

42 (48.8%)

 

64 (76.2%)

20 (23.8%)

 

 Hispanics

174 (61.7%)

108 (38.3%)

 

187 (66.6%)

94 (33.4%)

 

 Asian American

68 (60.2%)

45 (39.8%)

 

78 (70.3%)

33 (29.7%)

 

Country of birth

  

<0.001

  

0.67

 U.S.

463 (47.4%)

513 (52.6%)

 

689 (71.0%)

282 (29.0%)

 

 Other countries

205 (63.9%)

116 (36.1%)

 

230 (72.3%)

88 (27.7%)

 

Education

  

0.28

  

0.016

 <High school

134 (58.8%)

94 (41.2%)

 

170 (75.6%)

55 (24.4%)

 

 High school

116 (47.5%)

128 (52.5%)

 

181 (74.8%)

61 (25.2%)

 

 Some college

184 (49.1%)

191 (50.9%)

 

263 (70.5%)

110 (29.5%)

 

 College graduate or higher

234 (52.0%)

216 (48.0%)

 

305 (67.9%)

144 (32.1%)

 

Cigarette smoking status

  

0.70

  

0.74

 Never smokers

269 (52.2%)

246 (47.8%)

 

362 (70.8%)

149 (29.2%)

 

 Former smokers

291 (51.0%)

279 (49.0%)

 

412 (72.8%)

154 (27.2%)

 

 Current smokers

108 (50.9%)

104 (49.1%)

 

145 (68.4%)

67 (31.6%)

 

Body mass index (BMI)b

  

0.60

  

0.60

 Quartile1

207 (57.8%)

171 (45.2%)

 

266 (70.9%)

109 (29.1%)

 

 Quartile 2

158 (48.0%)

171 (52.0%)

 

236 (72.2%)

91 (27.8%)

 

 Quartile 3

150 (50.3%)

148 (49.7%)

 

219 (74.0%)

77 (26.0%)

 

 Quartile 4

153 (52.4%)

139 (47.6%)

 

198 (68.0%)

93 (32.0%)

 

Diabetes

  

0.42

  

0.91

 No

616 (51.8%)

572 (48.2%)

 

841 (71.2%)

340 (28.8%)

 

 Yes

52 (47.7%)

57 (52.3%)

 

78 (72.2%)

30 (27.8%)

 

Personal history of reflux symptoms

  

0.33

  

0.026

 No

582 (52.1%)

536 (47.9%)

 

804 (72.4%)

306 (27.6%)

 

 Yes

86 (48.0%)

93 (52.0%)

 

115 (64.2%)

64 (35.8%)

 
  1. aP values were estimated using Fisher’s exact test for binary variables, Mantel-Haenszel Chi-Square test for ordinal multi-level variables, and Chi-square test for nominal multi-level variables.
  2. bQuartile cut points for current BMI are ≤23, >23-25, >25- ≤ 28, >28 kg/m2 for males, and ≤22, >22-25, >25- ≤ 28.25, >28.25 kg/m2 for females.