Figure 3
From: Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
Drug concentration-dependent NF-κB response in colon cancer cells. SW480 (panel A), wild-type HCT116 (panel B), or p53-null HCT116 (panel C) cells were treated with the indicated concentrations of CPT, phleomycin (SW480 only), or erlotinib (HCT116 only) for 24 hours, and reporter assays were performed. The relative NF-κB activity indices (Y-axis) relative to vehicle (DMSO control), plotted against the drug concentrations (X-axis), are shown.