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Table 1 In vitro cytotoxicity of naproxen sodium and its derivatives

From: A novel naproxen derivative capable of displaying anti-cancer and anti-migratory properties against human breast cancer cells

24-h IC50, mM

Compound

MCF-7

MDA-MB-231

ER+, PR+

ER-, PR-, HER2/Neu-

Naproxen sodium (NS)

>5

~10

1

~1.8

~1.6

2

~3

~3

3

>10

>10

4

~2.7

~5.9

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BMC Cancer

ISSN: 1471-2407

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