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Table 3 Multivariable analysis of overall survival in patients with middle ear cancer

From: Prognostic models to predict overall and cause-specific survival for patients with middle ear cancer: a population-based analysis

 

Full model

Reduced model

Covariate

HR

95% CI

P-value

HR

95% CI

P-value

Age (70:45)

2.05

1.50-2.80

<0.001*

2.07

1.52-2.82

<0.001*

Sex

      

  Male

1

  

-

  

  Female

1.17

0.82-1.67

0.38

-

-

-

Race

      

  White

1

  

-

  

  Non White

1.11

0.73-1.68

0.64

-

-

-

Year of diagnosis (2000:1990)

0.89

0.70-1.14

0.35

-

-

-

Stage

      

  Localized

1

  

1

  

  Regional

2.01

1.23-3.28

0.005*

2.00

1.22-3.25

0.01*

  Distant

3.47

1.94-6.22

<0.001*

3.46

1.93-6.19

<0.001*

Radiation

      

  No

1

  

1

  

  Yes

1.52

1.00-2.30

0.05

1.66

1.12-2.46

0.01*

Histological types#

-

-

<0.001*

-

-

<0.001*

Surgery#

-

-

0.02*

-

-

0.02*

Histology × surgery

-

-

0.01*

-

-

0.01*

Surgery

      

  Squamous cell carcinoma

1

  

1

  

  Adenocarcinoma

0.23

0.11-0.47

<0.001*

0.24

0.12-0.50

<0.001*

  Others

0.67

0.39-1.17

0.15

0.70

0.40-1.20

0.20

No surgery

      

  Squamous cell carcinoma

1

  

1

  

  Adenocarcinoma

1.97

0.55-7.11

0.29

2.21

0.61-7.93

0.22

  Others

0.57

0.25-1.27

0.16

0.58

0.26-1.28

0.18

  1. Abbreviations: HR Hazard Ratio, CI Confidence Interval.
  2. #Hazard ratios for histology type are presented by surgery because of the significant interaction between these two covariates.
  3. *P <0.05.
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BMC Cancer

ISSN: 1471-2407

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