Table 2 The relative expression of EMT genes in E-cadherin deficient MCF10A cells
Epithelial markers | Mesenchymal markers | EMT Transcription factors | ||||||
|---|---|---|---|---|---|---|---|---|
Gene | FC | Adj. p value | Gene | FC | Adj. p value | Gene | FC | Adj. p value |
KRT8 | 1.4 | 7.67E-04 | CDH2 | -2.2 | 2.37E-04 | SNAI1 | -2.5 | 1.38E-02 |
KRT9 | 2.5 | 2.89E-02 | CDH11 | 1.4 | 3.11E-01 | SNAI2 | 1.0 | 5.83E-01 |
KRT18 | 1.4 | 3.86E-04 | VIM | 1.1 | 6.12E-02 | TWIST1 | -1.1 | 3.58E-01 |
CLDN1 | 3.1 | 3.45E-05 | FN1 | -7.2 | 1.78E-04 | TWIST2 | -1.2 | 4.20E-01 |
OCLN | 2.9 | 2.27E-05 | VTN | -1.3 | 6.07E-01 | ZEB1 | -1.7 | 1.23E-02 |
TJP3 | 1.9 | 4.69E-04 | CTNNB1 | 1.0 | 4.20E-01 | ZEB2 | -7.3 | 5.02E-05 |
CGN | 3.0 | 1.80E-04 | ACTA2 | 1.0 | 9.12E-01 | AKT2 | -1.1 | 8.54E-02 |
DSP | 1.0 | 9.87E-01 | ITGA5 | -1.2 | 8.75E-03 | MMP1 | 5.8 | 1.45E-02 |
SDC1 | 1.6 | 3.11E-05 | ITGAV | -1.4 | 2.11E-02 | MMP9 | 3.3 | 9.08E-04 |