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Table 3 Cox uni-and multivariable analysis of relative risk of death from colorectal cancer, rectal cancer, and left hemicolon cancer within 5 years by HES9 expression

From: Podocalyxin is a marker of poor prognosis in colorectal cancer

 

Colorectal cancer-specific survival

Left hemicolon cancer-specific survival

Rectal cancer-specific survival

 

HR (95% CI)

p-value

n (events)

HR (95% CI)

p-value

n (events)

HR (95% CI)

p-value

n (events)

 

Univariable

        

HES9 low

1.00

 

723 (266)

1.00

 

534 (194)

1.00

 

351 (125)

   High

2.00 (1.31–3.06)

0.001

44 (23)

2.60 (1.45–4.66)

0.001

21 (12)

3.03 (1.54–5.60)

0.001

16 (9)

 

Multivariable

        

HES9 low

1.00

 

719 (266)

1.00

 

532 (194)

1.00

 

351 (125)

   High

1.82 (1.15–2.86)

0.01

44 (23)

2.59 (1.41–4.88)

0.002

21 (12)

2.69 (1.30–5.54)

0.007

16 (9)

  1. Abbreviations: CI confidence interval, HR Hazard ratio. Multivariable analysis included adjustment for gender, age (>/≤65 years), Dukes class, differentiation grade (G1/2 vs G3/4). MAb HES9 recognises PODXL protein.