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Table 1 Association of AEG-1 expression with clinicopathological characteristics of PDAC patients

From: Expression of astrocyte elevated gene-1 (AEG-1) as a biomarker for aggressive pancreatic ductal adenocarcinoma

Characteristics

AEG-1 expression

 

Low or none N (%)

High N (%)

Chi-square test, P-value

Gender

Male

31 (29.52)

32 (30.48)

0.172

 

Female

15 (14.29)

27 (25.71)

 

Age (years)

< 60

23 (21.90)

20 (19.05)

0.096

 

≥ 60

23 (21.90)

39 (37.15)

 

Localization

Head of the pancreas

28 (26.67)

46 (43.81)

0.057

 

Body/tail of the pancreas

18 (17.14)

13 (12.38)

 

Tumor size

≤ 2

10 (9.52)

4 (3.81)

0.025

 

> 2

36 (34.29)

55 (52.38)

 

Clinical Stage

I

19 (18.10)

12 (11.43)

0.004

II

6 (5.71)

4 (3.81)

III

15 (14.29)

25 (23.81)

 

IV

6 (5.71)

18 (17.14)

 

T classification

T1

10 (9.52)

4 (3.81)

0.006

T2

29 (27.62)

33 (31.43)

T3

3 (2.85)

11 (10.48)

 

T4

4 (3.81)

11 (10.48)

 

N classification

N0

29 (27.62)

20 (19.05)

0.003

 

N1

17 (16.19)

39 (37.14)

 

M classification

No

43 (40.95)

43 (40.95)

0.007

 

Yes

3 (2.86)

16 (15.24)

 

Histological Grades

Well-differentiated

1 (0.95)

2 (1.90)

0.052

Moderately differentiated

40 (30.10)

45 (42.86)

 

Poorly differentiated

4 (3.81)

13 (12.38)

 

Histological Types

Classical ductal adenocarcinoma

43 (40.95)

48 (45.73)

0.097

Adenosquamous carcinomas

2 (1.90)

5 (4.76)

Undifferentiated carcinomas

0 (1.00)

4 (3.81)

 

Mixed ducal-neuroendocrine carcinoma

1 (0.95)

2 (1.90)

 

Alcohol drinking

No

24 (22.86)

40 (38.09)

0.104

 

Yes

22 (20.95)

19 (18.10)

 

Tobacco smoking

No

28 (26.67)

28 (26.67)

0.172

Yes

18 (17.14)

31 (29.52)