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Figure 1 | BMC Cancer

Figure 1

From: First evidence of a large CHEK2 duplication involved in cancer predisposition in an Italian family with hereditary breast cancer

Figure 1

Pedigree of the family with duplication in CHEK2. Black symbols indicate breast cancer and grey symbols indicate other type of tumours (see text); the proband is indicated by an arrow; members of the family submitted to the genetic test are indicated by +/− for mutation carriers or −/− for non-mutation carriers; the vertical bar indicates unaffected mutation carriers.

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