Figure 1From: First evidence of a large CHEK2 duplication involved in cancer predisposition in an Italian family with hereditary breast cancer Pedigree of the family with duplication in CHEK2. Black symbols indicate breast cancer and grey symbols indicate other type of tumours (see text); the proband is indicated by an arrow; members of the family submitted to the genetic test are indicated by +/− for mutation carriers or −/− for non-mutation carriers; the vertical bar indicates unaffected mutation carriers.Back to article page