Figure 2

Network of eligible trials where center node represents the reference comparator: Gemcitabine. Circle size is proportionate to the number of patients, thickness of line represents number of trials per comparison and distance of circle to reference comparator (gemcitabine) is proportionate to year of publication where 1 cm = 2 years. Gem = gemcitabine. 5FU = 5-fluorouacil. FA = Folinic Acid. Erlo = erlotinib. Epi = epirubicin. Bev = bevacizumab. Cape = capecitabine. Soraf = sorafinib. M = marismastat. Cis = cisplatin. Irino = irinotecan. Oxali = oxaliplatin. Tipif = tipifarnib. Cetux = cetuximab. NAB-P = NAB-Paclitaxel.