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Table 1 Summary of the multivariate longitudinal data analysis

From: Oncogenic MicroRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum

A) miR-155

Parameter

Estimate

Standard error

p -value

Ī² I

0.61774

0.06440

< 2e-16

Ī² II

āˆ’0.24024

0.05617

1.89e-05

Ī² III

āˆ’0.34474

0.05684

1.32e-09

Ī² C

āˆ’0.51148

0.11103

4.10e-06

Ī² L

āˆ’0.18353

0.08245

0.026

B) miR-19a

Parameter

Estimate

Standard error

p -value

Ī² I

0.60941

0.04843

< 2e-16

Ī² II

0.03224

0.03187

0.31183

Ī² III

0.09981

0.03804

0.00869

Ī² C

0.34506

0.11439

0.00256

Ī² L

0.15711

0.07041

0.02567

C) miR-181b

Parameter

Estimate

Standard error

p -value

Ī² I

0.70370

0.05176

< 2e-16

Ī² II

0.17814

0.03917

5.41e-06

Ī² III

0.17263

0.03884

8.80e-06

Ī² C

0.27792

0.10095

0.0059

Ī² L

0.16588

0.07403

0.0250

D) miR-24

Parameter

Estimate

Standard error

p -value

Ī² I

0.50276

0.06718

7.19e-14

Ī² II

āˆ’0.14807

0.05429

0.00638

Ī² III

āˆ’0.12527

0.05527

0.02343

Ī² C

āˆ’0.34034

0.11512

0.00311

Ī² L

āˆ’0.22631

0.08774

0.00990

  1. Presented are parameters to calculate conditional expectation of the miRā€™s serum level for each BC patient/control at particular time point and their estimate values, their standard errors, and corresponding p-values for levels of miR-155 (A), miR-19a (B), miR-181b (C), and miR-24 (D), all relative to let-7a, in EBC sera. Parameters of oncomiR level: Ī² I : time point I, Ī² II : the difference between time points I and II, Ī² III : the difference between time points I and III, Ī² C : the difference between time point I and healthy control, and Ī² L : the difference between high risk and low risk EBC patients.
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BMC Cancer

ISSN: 1471-2407

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