Figure 8From: Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells Loss of Wee1 activity results in incorrect initiation of DNA synthesis in NCI-H1299 cells but not A549 cells. NCI-H1299 and A549 cells were treated with 5 nM non-targeting (N1) or Wee1 (#8) siRNAs and stained for DNA content (X-axis) and EdU incorporation (Y-axis) to mark cells in S-phase. Samples were taken at both 24 and 48Â hours after treatment.Back to article page