Increased health care utilization by survivors of childhood lymphoblastic leukemia is confined to those treated with cranial or total body irradiation: a case cohort study

Table 3 Distribution (percentage) among 5-year survivors of acute lymphoblastic leukemia and controls by number of hospital contacts and days in hospital

	Chemotherapy only	CRT	TBI	Relapse	ALL survivors	Controls	p-value²
	n = 104	n = 95	n = 14	n = 24	n = 213	n = 10,650	p-value²
At least one hospital contact¹	35.9	59.4	78.6	66.7	49.3	34.1	< 0.001
Total number of hospital contacts
1–2	25.2	24.0	50.0	33.3	28.2	26.6	< 0.001
≥3	10.7	35.4	28.6	33.3	21.1	7.6	< 0.001
Total number of days in hospital
1–7 days	24.3	26.0	50.0	25.0	26.8	25.7	< 0.001
8–30 days	7.8	18.8	14.3	12.5	13.1	5.9
> 30 days	3.9	14.6	14.3	29.2	9.4	2.5

¹Hospital contacts from 5 years after the diagnosis of ALL, or the corresponding date for the controls, until the end of follow-up. In the case of a relapse, hospital contacts within the first five yeas after diagnosis of relapse were excluded, ²p-value for comparison between all survivors and controls. Abbreviations: CRT received cranial irradiation in addition to chemotherapy, TBI received total body irradiation in addition to chemotherapy, including three cases who, in addition, received cranial irradiation.

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