Figure 5
Effect of PGE 2 and forskolin on DNA synthesis and cAMP accumulation. A. Effect of increasing concentrations of PGE2 on PDGF-stimulated DNA synthesis. Results are presented as mean ± S.E.M. of four experiments. B. Effect of 1 μM forskolin on PDGF- stimulated DNA synthesis. Results are presented as mean ± S.E.M. of four experiments. C. Time-dependent effect of 1 μM PGE2 on cAMP accumulation in the absence of IBMX. Results are from one typical of four experiments and are presented as mean ± S.E.M. of triplicates. D. Time-dependent effect of 5 μM forskolin on cAMP accumulation in the absence of IBMX. Results are from one typical of four experiments and are presented as mean ± S.E.M. of triplicates. * Sign. different from control. ** Sign. different from PDGF alone.