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Table 4 Univariate and multivariate analysis of disease-free survival

From: Carbonic anhydrase 9 is associated with chemosensitivity and prognosis in breast cancer patients treated with taxane and anthracycline

Parameter

 

Univariate analysis

  

Multivariate analysis

 
 

Odds ratio

95% CI

p value

Odds ratio

95% CI

p value

CA9 expression in CNB specimens

      

positive vs negative

4.44

1.80-10.9

0.001

2.32

0.88-6.08

0.089

CA9 expression in resected tissues

      

positive vs negative

2.63

1.21-5.70

0.014

2.39

1.04-5.49

0.041

Tumor size

      

≥ 4 cm vs < 4 cm

2.46

1.11-5.45

0.026

1.61

0.65-3.97

0.302

Lymph node status

      

N1-3 vs N0

3.00

1.42-6.35

0.004

0.97

0.38-2.47

0.955

Lymph-vascular invasion

      

positive vs negative

4.22

1.99-8.92

<0.001

2.75

1.11-6.62

0.028

ER

      

positive vs negative

0.91

0.43-1.94

0.807

   

PgR

      

positive vs negative

0.95

0.45-2.02

0.905

   

HER2

      

positive vs negative

1.36

0.59-3.11

0.46

   

Clinical response

      

Responder vs non-responder

0.88

0.37-2.08

0.78

   

Pathological response

      

Responder vs non-responder

0.29

0.12-0.67

0.004

1.03

0.38-2.78

0.953

pCR vs non-pCR

0.19

0.45-0.81

0.024

1.34

0.27-6.62

0.722

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BMC Cancer

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