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Table 5 EORTC QLQ-H&N35 scales and TN stage

From: Influence of pain severity on the quality of life in patients with head and neck cancer before antineoplastic therapy

 

T*

 

N**

 
 

T1

T2

T3

T4

 

N0

N+

 

(n = 25)

(n = 30)

(n = 24)

(n = 48)

(n = 43)

(n = 84)

EORTC QLQ –H&N35

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

p

Mean (SD)

Mean (SD)

p

Pain

7.6 (13.5)

29.4 (26.5)

28.4 (28.2)

44.2 (34.5)

<0.001

24.0 (29.2)

43.4 (30.7)

<0.001

Swallowing

2.0 (6.0)

32.7 (32.8)

31.2 (33.5)

48.4 (33.3)

<0.001

22.8 (32.0)

50.9 (30.1)

<0.001

Senses problems

15.3 (33.6)

10.0 (21.2)

16.6 (28.2)

19 (35.4)

0.926

14.6 (30,6)

18.2 (31.2)

0.362

Speech problems

13.7 (25.7)

15.1 (22.5)

30.5 (33.4)

31.2 (31.2)

0.029

20.8 (27.9)

29.7 (32.2)

0.240

Trouble with social eating

2.0 (6.9)

19.1 (26.6)

25.6 (29.8)

34.0 (30.5)

<0.001

14.4 (23.5)

38.5 (31.2)

<0.001

Trouble with social contact

5.0 (7.2)

7.7 (14.0)

18.8 (20.4)

13.8 (20.1)

0.005

7.4 (10.7)

19.8 (24.2)

0.001

Less sexuality

12.0 (25.2)

16.1 (29.1)

29.1 (43.1)

30.5 (40.5)

0.211

14.0 (29.1)

41.0 (42.9)

<0.001

Teeth

4.0 (14.6)

16.6 (34.7)

12.5 (29.1)

29.1 (42.1)

0.046

10.3 (26.8)

33.3 (43.6)

0.001

Opening mouth

1.3 (6.6)

10.0 (27.8)

19.4 (30.9)

36.1 (42.8)

<0.001

15.4 (30.3)

28.6 (42.1)

0.112

Dry mouth

25.3 (38.8)

27.7 (37.2)

18.0 (36.7)

18.7 (34.3)

0.416

22.2 (36.7)

21.7 (35.5)

0.946

Sticky saliva

13.3 (27.2)

37.7 (40.8)

34.7 (45.5)

62.5 (41.6)

<0.001

35.3 (40.5)

54.2 (46.5)

0.024

Coughing

20.0 (25.4)

26.6 (33.2)

22.2 (27.2)

22.9 (30.0)

0.955

21.4 (28.6)

26.3 (30.4)

0.337

Felt ill

8.0 (19.9)

11.1 (26.7)

23.6 (38.6)

27.7 (40.8)

0.125

13.8 (29.3)

29.4 (41.9)

0.042

Pain killers

28.0 (45.8)

70.0 (46.6)

83.3 (38.0)

77.0 (42.4)

<0.001

60.7 (49.1)

79.0 (41.1)

0.038

Nutritional supplements

8.0 (27.6)

6.6 (25.3)

0

6.2 (24.4)

0.613

4.7 (21.4)

6.9 (25.7)

0.606

Feeding tube

0

0

0

0

-

0

0

-

Weight loss

4.0 (20.0)

40.0 (49.8)

54.1 (50.8)

70.8 (45.9)

<0.001

34.5 (47.8)

72.0 (45.3)

<0.001

Weight gain

28.0 (45.8)

23.3 (43.0)

8.3 (28.2)

6.2 (24.4)

0.035

16.6 (37.4)

11.6 (32.4)

0.453

  1. *Kruskal-Wallis test, **Mann Whitney test. Abbreviations: T, Tumor size; N, Lymph node involvement.
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