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Table 1 ERα/ERβ1 expression patterns between PTC and NTG tissues from female patients of reproductive age a

From: Differential expression patterns and clinical significance of estrogen receptor-α and β in papillary thyroid carcinoma

 

PTC (n = 50)

NTG (n = 30)

P-value

ERα

Positive percentage

30/50 (60.0%)

2/30 (6.7%)

0.000

Total score b

3.44 ± 2.80

0.27 ± 1.05

0.000

Subcellular localization

Nu

22/30 (73.3%)

2/2 (100%)

0.000

Nu + Cyto

6/30 (20.0%)

0

Cyto

2/30 (6.7%)

0

ERβ1

Positive percentage

48/50 (96.0%)

28/30 (93.3%)

0.596

Total score

6.36 ± 1.64

7.03 ± 1.85

0.001

Subcellular localization

Nu

7/48 (14.6%)

23/28 (82.1%)

0.000

Nu + Cyto

36/48 (75.0%)

5/28 (17.9%)

Cyto

5/48 (10.4%)

0

  1. aThe female patients of reproductive age were 18–45 years old. bTotal score was calculated from the sum of the proportion staining score and the intensity score to reflect the expression level, which is given as mean ± standard deviation (S.D.). PTC, papillary thyroid cancer; NTG, nodular thyroid goiter; Nu, exclusively nuclear staining; Nu + Cyto, combined nuclear and cytoplasmic staining; Cyto, exclusively cytoplasmic staining.