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Table 1 Clinicopathological characteristics of 458 patients with single SHCC

From: Microvascular invasion (MVI) is a poorer prognostic predictor for small hepatocellular carcinoma

Clinicopathological features

Valuea

Age(yr), mean (median)

52.65 (52)

Sex

 

 Male

384 (84.0%)

 Female

74 (16.0%)

Pre-operation AFP value ≥200 ug/mla

147 (33.0%)

Post-operation AFP value ≥20 ug/mlb

178 (63.6%)

Virus infectionc

 

 No virus

30 (6.6%)

 HBV

421 (92.0%)

 HCV

4 (1.0%)

 HBV&HCV

1 (0.2%)

 HBV&HEV

1 (0.2%)

Cirrhosis

 

 Y

411 (89.7%)

 N

47 (10.3%)

Capsulary formationd

 

 Y

249 (55.5%)

 N

200 (44.5%)

Tumor bordere

 

 Clearly

434 (97.3%)

 Vaguely

12 (2.7%)

Tumor histological differentiation

 

 Well differentiated

14 (3.1%)

 Moderately differentiated

345 (75.3%)

 Poorly differentiated

99 (21.6%)

Tumor microscopic manifestation

 

 MVI

 

  Y

83 (18.1%)

  N

375 (81.9%)

Tumor infiltrative lymphocytes

 

 ≥50/HPF

84 (18.3%)

 <50/HPF

374 (81.7%)

Clear cell subtype

 

 Y

23 (5.0%)

 N

435 (95.0%)

Tumor fatty change

 

 Y

15 (3.3%)

 N

443 (96.7%)

Large cell dyplastic change

 

 Y

36 (7.9%)

 N

422 (92.1%)

Peritumor liver fatty change

 

 Y

90 (19.7%)

 N

368 (80.3%)

PFS(mo),median(range)

53.00 (4-75)

OS(mo),median(range)

54.00 (21-75)

  1. aMissing data in 12 cases.
  2. bMissing data in 178 cases.
  3. cMissing data in 1 cases.
  4. dMissing data in 9 cases.
  5. eMissing data in 12 cases.
  6. AFP a-fetoprotein, MVI microvascular invasion.
  7. aValues are expressed as n(%) or median(range).