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Table 3 Multivariate analysis identified elective nephron-sparing surgery (ePN) as an independent prognostic factor for overall survival in patients with pT ≤ 3a RCC and no detectable metastasis at the time of surgery including all participating centers

From: Survival advantage of partial over radical nephrectomy in patients presenting with localized renal cell carcinoma

Variable

P value

HR (95% CI)

Age [in years] 1

< 0.001

1.06 (1.05-1.06)

Sex

0.005

 

 Female

 

1 (Reference)

 Male

 

1.21 (1.06-1.39)

Histological subtype

0.25

 

 ccRCC

 

1 (Reference)

 Non-ccRCC

 

0.90 (0.76-1.07)

Differentiation

< 0.001

 

 G1-2

 

1 (Reference)

 G3-4

 

1.88 (1.57-2.26)

Tumor diameter [in cm]

< 0.001

1.07 (1.04-1.09)

Surgical procedure

0.02

 

 RN

 

1 (Reference)

 ePN

0.008

0.79 (0.66-0.94)

 iPN

0.62

1.07 (0.83-1.38)

Year of surgery [in years]

0.01

0.99 (0.98-0.99)

  1. 1At the time of surgery. RCC = renal cell carcinoma, ccRCC = clear cell RCC, G = tumor grade, RN = radical nephrectomy, ePN = elective partial nephrectomy, iPN = imperative partial nephrectomy.