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Table 6 Univariate and multivariate survival analyses by pN stage in patients with pT4b stage CC

From: Solitary lymph node metastasis is a distinct subset of colon cancer associated with good survival: a retrospective study of surveillance, epidemiology, and end-results population-based data

 

Univariate analysis

Multivariate analysis

Variable

5-year CCS

Log rank χ 2test

P

HR (95% CI)

P

Years of diagnosis

 

37.575

<0.001

 

0.001

 1988-1993

44.4%

  

Reference

 

 1994-1999

49.2%

  

0.905 (0.807-1.014)

 

 2000-2003

55.7%

  

0.809 (0.726-0.902)

 

Sex

 

1.163

0.281

 

NI

 Male

51.9%

    

 Female

50.7%

    

Age

 

41.821

<0.001

 

<0.001

 <60

56.7%

  

Reference

 

 ≥60

48.0%

  

1.329 (1.213-1.456)

 

Race

 

19.460

<0.001

 

<0.001

 White

52.0%

  

Reference

 

 Black

42.3%

  

1.337 (1.175-1.522)

 

 Othera

56.4%

  

0.920 (0.781-1.084)

 

Grade

 

48.208

<0.001

 

<0.001

 High/moderate

54.3%

  

Reference

 

 Poor/anaplastic

44.8%

  

1.343 (1.219-1.479)

 

 Unknown

41.7%

  

1.324 (1.094-1.601)

 

Histotype

 

0.024

0.877

 

NI

 Adenocarcinoma

51.2%

    

Mucinous/signet ring cell

51.4%

    

No. of LNs dissected

 

158.496

<0.001

 

<0.001

 <12

42.4%

  

Reference

 

 ≥12

60.4%

  

0.598 (0.548-0.653)

 

LNs status

 

1213.378

<0.001

 

<0.001

 N0 (pIIC)

60.6%

  

0.596 (0.534-0.666)

 

 N1a

40.5%

  

Reference

 

 N1b

34.1%

  

1.201 (1.062-1.358)

 
  1. aOther includes American Indian/Alaska native, Asian/Pacific Islander, and unknown.
  2. NI: not included in multivariate survival analyses.
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BMC Cancer

ISSN: 1471-2407

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