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Table 4 Univariate and multivariate survival analyses by pN stage in patients with pT3 stage CC

From: Solitary lymph node metastasis is a distinct subset of colon cancer associated with good survival: a retrospective study of surveillance, epidemiology, and end-results population-based data

 

Univariate analysis

Multivariate analysis

Variable

5-year CCS

Log rank χ 2test

P

HR (95% CI)

P

Years of diagnosis

 

39.995

<0.001

 

<0.001

 1988-1993

80.3%

  

Reference

 

 1994-1999

82.6%

  

0.874 (0.808-0.946)

 

 2000-2003

84.6%

  

0.820 (0.763-0.881)

 

Sex

 

25.387

<0.001

 

<0.001

 Male

82.7%

  

Reference

 

 Female

84.3%

  

0.855 (0.811-0.901)

 

Age

 

169.293

<0.001

 

<0.001

 <60

87.3%

  

Reference

 

 ≥60

81.7%

  

1.542 (1.453-1.638)

 

Race

 

103.809

<0.001

 

<0.001

 White

84.1%

  

Reference

 

 Black

77.7%

  

1.461 (1.355-1.574)

 

 Othera

86.2%

  

0.801 (0.733-0.896)

 

Grade

 

15.823

<0.001

 

0.032

 High/moderate

84.0%

  

Reference

 

 Poor/anaplastic

80.8%

  

1.098 (1.024-1.178)

 

 Unknown

83.5%

  

1.003 (0.851-1.182)

 

Histotype

 

1.212

0.271

 

NI

 Adenocarcinoma

83.5%

    

Mucinous/signet ring cell

83.8%

    

No. of LNs dissected

 

270.983

<0.001

 

<0.001

 <12

80.0%

  

Reference

 

 ≥12

86.8%

  

0.668 (0.633-0.705)

 

LNs status

 

1209.713

<0.001

 

<0.001

 N0 (pIIA)

88.4%

  

0.510 (0.476-0.546)

 

 N1a

77.8%

  

Reference

 

 N1b

69.4%

  

1.449 (1.334-1.561)

 
  1. aOther includes American Indian/Alaska native, Asian/Pacific Islander, and unknown.
  2. NI: not included in multivariate survival analyses.